L.B. Bohle Maschinen und Verfahren GmbH

Pharmaceutical film coating, i.e. coating of particles, is a crucial process in pharmaceutical production. All tablet coating processes are based on three steps:

• Spraying
• Blending
• Drying

Tablets are mainly coated to achieve a modification of substance release, protect the substance against light and moisture or to cover the bitter flavor of the tablet formula. Compatibility of the dosage form is relevant as well. Coated tablets are easier to swallow and can be better distinguished due to different colors. Processing active ingredients in tablet coating, the active ingredient coating, is becoming more and more relevant.
 
L.B. Bohle has been the technology leader in the development and production of film coating systems for the pharmaceutical industry. The Bohle BFC Film Coater is the high-end version of the L.B. Bohle coaters, standing out with high efficiency, optimized output, and lowest suspension loss.

L.B. Bohle film coating technology is based on three essential and unique properties:

• The drum geometry
• The patented twin spirals
• The air system

Best process management
All L.B. Bohle coaters guarantee best-of-class product processing and excellent cost effectiveness. The flat tablet bed in a long drum geometry, as well as continuous adjustment of the inclination angle ensure optimal movement of the cores. The systematic compulsory guide in the drum enables continuous product movement. There is no tablet twinning, Both solid and paint losses are kept low.
Lowest suspension losses
Innovative concepts for processes, as well as for cleaning, improve the tablet coater functionality and deliver outstanding results. The type of air system reveals significant process-related advantages. The risk of spray-drying at the suspension is a thing of the past. This reduces spray losses and improves coating structure.

Tablets are handled more carefully thanks to the pan geometry and the blending and conveyor elements. Through change of direction of pan rotation, tablets can be discharged completely and without containments.
 
Benefits of the Film Coater 

• Patented helical baffles
• Mixing at two levels using counter-rotation
• Large spray surface, length: Diameter >1
• Prevention of spray-drying, heating only in tablet bed
• CIP-cleaning
• Guaranteed scale-up
• Better performancer by up to 40%
• Best uniformity: RSD < 2%
• Lowest spray losses < 5%