L.B. Bohle Maschinen und Verfahren GmbH

Dry Granulation – BRC

Continuous dry granulation has been an established process in the pharmaceutical industry for decades and is used for more than just moisture- or temperature-sensitive products.
Unlike classic wet granulation methods, this process does not require any energy-intensive drying processes; this avoids the need for large investments in systems and production facilities, and lowers the costs per batch.

Dry granulation is frequently the preferred approach for very bulky or moisture-sensitive products. L.B. Bohle’s BRC granulators are suitable for continuous production and can be integrated with Process Analytical Technology (PAT). Because of this, the BRC series granulators offer flexibility for integration into a wide variety of production scenarios.
  
Granulation with the L.B. Bohle Dry Granulator

• Minimal material loss due to precise control of the compression force with an innovative electromechanical roller drive
• Maintaining constant ribbon properties
• Easy to use and quick set-up
• Hygienic design and effective cleaning via WIP nozzles (‘washing in place’ process)
• Versatile and gentle particle size calibration with integrated Bohle Turbo Sieve (BTS)
• Particle size calibration with integrated Bohle rotation sieve (BRS)
• Optional PAT integration
• Optional containment equipment including sampling